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I didn't realize this kind of targeting would cut down on other advertisers being placed in an ad. For example, instead of four advertsiers shown in a 300 x 250 text block ad only the targeted advertiser would be shown?
Whenever you go to change the name for the channel being targeted, Adsense warns you and gives you an option to click to see the 'past 7 days earnings' for this ad placement. Not sure how detailed it is though, as far as if it is worthwhile or not.
There really aren't a lot of articles on the net I've been able to find on this topic.
Cheers,
[edited by: CWebguy at 1:43 pm (utc) on April 29, 2009]