Windows 10 Creators update will test the preventing installation of apps that are not from the Windows Store.
There will be an option to "Prefer apps for the Store, but allow from anywhere.

It's the wild west out there for bloatware and apps, and it firmly shifts the responsibility back on the user should a problem app be installed.

The latest preview of Windows 10 gives users the option to prevent classic Win32 apps, which aren't available in the Windows 10 Store, from installing on a device. This measure could provide a significant defense against bloatware and malware both for consumers and the enterprise. Windows 10 Creators Update Tests Windows Store Only App Installation [zdnet.com]