On my sites, site targeted ads rarely receive a click. I guess this is because the ads are often waaaay off topic, e.g. an ad for swimming pools sold in the U.S. on a travel page on Elbonia. Who might click such an ad? People who look for information on Elbonia, thinking - "heck, I'd better get a swimming pool instead of wasting money to travel to Elbonia!"? - People who are looking for swimming pools but decided to look at a page on Elbonia?

I guess some advertisers have not fully understood how site targeting works.

The payout can be ignored completely, so I theory I would care whether I am being site targeted or not. But fortunately, site targeting has such a low proportion of all ads being served on my sites that I simply do not care. :-)